SELECTIVE BLOCKADE OF SPINAL D2DR BY LEVO-CORYDALMINE ATTENUATES MORPHINE TOLERANCE VIA SUPPRESSING PI3K/AKT-MAPK SIGNALING IN A MOR-DEPENDENT MANNER

Selective blockade of spinal D2DR by levo-corydalmine attenuates morphine tolerance via suppressing PI3K/Akt-MAPK signaling in a MOR-dependent manner

Pain medicine: why blocking dopamine receptors alleviates morphine tolerance By blocking dopamine receptors located in the spinal cord, a compound found in a traditional Chinese herbal medicine may help mitigate tolerance to morphine, a common problem read more among cancer patients who regularly take the opioid painkiller.A team led by Ji-Hua Liu

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Platelet-Rich Fibrin Used in Regenerative Endodontics and Dentistry: Current Uses, Limitations, and Future Recommendations for Application

Regenerative endodontics has introduced numerous procedures such as pulp implantation, revascularization, and postnatal stem cell therapy.Revascularization has been successfully implemented clinically nowadays, thus providing dentists 2006 nissan altima radio with outrageous results.Platelet-rich fibrin (PRF) used either alone or along with bone gr

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Brief communication: Accurate and autonomous snow water equivalent measurements using a cosmic ray sensor on a Himalayan glacier

We analyze snow water equivalent (SWE) measurements from a cosmic ray sensor (CRS) on the lower accumulation area of Mera Glacier (central Himalaya, Nepal) between November 2019 and November 2021.The CRS aligned well with field observations and revealed accumulation in pre-monsoon and monsoon observations, followed by ablation in post-monsoon and w

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Data Mining for Identification of Forkhead Box O (FOXO3a) in Different Organisms Using Nucleotide and Tandem Repeat Sequences

Background: Deregulation of FOXO3a gene which belongs to Forkhead box O (FOXO) transcription simply boho classroom factors, can cause cancer (e.g.breast cancer).FOXO factors have important role in ubiquitination, acetylation, de-acetylation, protein-protein interactions and phosphorylation.Understanding the regulation and mechanisms of FOXO3a can l

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Modeling and stabilization of eccentric gravity machinery

In general, eccentric gravity machinery is a rotation mechanism with eccentric pendulum mechanism, which can be used to convert continuously kinetic energy radio birdman tshirt generated by gravity energy to electric energy.However, a stable rotated velocity of the eccentric gravity machinery is difficult to be achieved only using gravity energy.In

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